Peritoneal mesothelial cell biology in peritoneal dialysis
نویسندگان
چکیده
منابع مشابه
Peritoneal Dialysis
La,dialyse peritoneale constitue une methode d,epuration extra-renale simple,efficqCe et d,un prix de revient modere. La dialyse peritoneale,ne necestite aueuneinstalation complexe,peut-etre consideree comme une methode de reanimation non specialisedont la vulgarosation doit permettre: De traiter surplace d,une maniere intensive et prophylactique les nombreuses insuffisances renales aiPue...
متن کاملMembrane Biology During Peritoneal Dialysis
Peritoneal dialysis (PD) is a life-supporting renal replacement therapy used by 10-15% of patients with end-stage renal failure worldwide. The success of long-term PD depends entirely on the longevity and integrity of the peritoneal membrane. The peritoneum is covered by a mesothelial monolayer beneath which is a basement membrane and submesothelial layer that contains collagen, fibroblasts, ad...
متن کاملEffect of high glucose on peritoneal mesothelial cell biology.
OBJECTIVE This study reviews evidence that implicates high glucose (HG) in the pathogenesis of peritoneal fibrosis and proposes mechanisms potentially involved in the HG-induced peritoneal fibrosis that is observed in long-term peritoneal dialysis (PD) patients. DESIGN Selected Western literature is reviewed, examining the effect of HG on rat or human peritoneal mesothelial cell (HPMC) biolog...
متن کاملPeritoneal dialysis fluids can alter HSP expression in human peritoneal mesothelial cells.
BACKGROUND Acute exposure of mesothelial cells to peritoneal dialysis fluid (PDF) has been shown not only to result in injury but also to induce cytoprotective heat shock proteins (HSP). The aim of the present study was to evaluate the expression of HSP in a more chronic in vitro PDF exposure system, searching for a role of glucose degradation products (GDP). METHODS Human peritoneal mesothel...
متن کاملTamoxifen Ameliorates Peritoneal Membrane Damage by Blocking Mesothelial to Mesenchymal Transition in Peritoneal Dialysis
Mesothelial-to-mesenchymal transition (MMT) is an auto-regulated physiological process of tissue repair that in uncontrolled conditions such as peritoneal dialysis (PD) can lead to peritoneal fibrosis. The maximum expression of peritoneal fibrosis induced by PD fluids and other peritoneal processes is the encapsulating peritoneal sclerosis (EPS) for which no specific treatment exists. Tamoxifen...
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ژورنال
عنوان ژورنال: Nephrology
سال: 2002
ISSN: 1320-5358,1440-1797
DOI: 10.1046/j.1440-1797.2002.00122.x